PLGF (Placenta Growth Factor) is a new marker for Preeclampsia.Angiogenesis and vascular transformation are important processes in the normal development of the placenta. Abnormal angiogenesis and vascular transformation are considered to be one of the main reasons for preeclamptic pregnancies and intrauterine growth factor (PLGF), a member of the VEGF family, is produced chiefly by the placenta and is a potent angiogenic factor.The corresponding receptor, the soluble fms-like tyrosine kinase-1 is considered to have anti-angiogenic properties. Now a new PLGF-ELISA kit for routine diagnostics is available, which offers new possibilities in the prediction of preeclampsia.
The PLGF ELISA allows the early detection (15th week of pregnancy) of the developmental risk factors of pre-eclampsia and is therefore an important new tool in the health protection of mother and child.